A modified protein appears to trigger lung fibrosis after environmental exposure

The triggers and causes of a severe scarring disease of the lungs—idiopathic pulmonary fibrosis, or IPF—remain unclear. Now, research published in Science Translational Medicine shows how cadmium and carbon black can trigger lung macrophages to produce a modified protein, citrullinated vimentin, or cit‑vim, which leads to lung fibrosis. Researchers from the University of Alabama at […]

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Anti-inflammatory therapies have potential to prevent heart disease in the elderly

Therapies that soothe inflammation could be an effective way to prevent heart disease in people with a common age-related blood condition, according to a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons. The researchers identified how the blood condition, called clonal hematopoiesis, worsens atherosclerosis, and their findings suggest that an […]

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